N‐heterocyclic carbene‐catalyzed activation of ynals for rapid synthesis of pyridine derivatives with important utilities has been reported. This successful strategy using NHC‐bound alkynyl acyl azolium as the key intermediate further improved the application of N‐Ts 2‐aminoacrylate as a nucleophile. Importantly, this work introduces an ester substituent to pyridines that could be easily transformed to other functional groups.

中文翻译：

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N-杂环卡宾催化的Ynals的功能性吡啶的构建。

据报道，N-杂环卡宾催化的羰基活化具有重要的实用价值，可快速合成吡啶衍生物。这种使用NHC结合的炔基酰基偶氮鎓作为关键中间体的成功策略进一步改善了N -Ts 2-氨基丙烯酸酯作为亲核试剂的应用。重要的是，这项工作将吡啶的酯取代基引入了吡啶，可以很容易地转化为其他官能团。