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Pediatric Fatal Chromobacterium violaceum in Tanzania: The First Documented Case
SN Comprehensive Clinical Medicine Pub Date : 2019-11-19 , DOI: 10.1007/s42399-019-00177-z
George M. Bwire , Nsiande Lema , Robert Makala , Anna Magembe , Fredrick Francs , James Kalabashanga , Mtebe Majigo

Chomobacterium violaceum is a gram-negative bacteria, which inhabit soil or water and rarely causes disease in human. The first case of C. violaceum bacteria isolated from a 6-month-old male admitted at Muhimbili National Hospital, Tanzania, is reported. A patient had a high fever (39.2 °C), vomiting with no history of convulsion, loss of consciousness, skin or joint infection, cough or difficulty in breathing, neither ear pain nor ear discharge. On admission, blood examination found no malaria parasites with normal urinalysis. Venous blood samples were taken for blood culture followed by empirical therapy with ceftriaxone 800 mg daily, intravenous paracetamol 125 mg stat then 125 mg 8 hourly was initiated. On the second day post-admission, the patient succumbed to septic shock before blood culture results were available. In conclusion, cultural and biochemical identification of a blood culture revealed C. violaceum infection.

中文翻译:

坦桑尼亚的小儿致命性紫色杆菌:第一个有记录的病例

紫丁酸杆菌是革兰氏阴性细菌,它生活在土壤或水中,很少引起人类疾病。第一例紫堇据报道,该细菌是从坦桑尼亚Muhimbili国家医院住院的6个月大男性分离得到的。患者发高烧(39.2°C),呕吐,无惊厥史,无意识丧失,皮肤或关节感染,咳嗽或呼吸困难,无耳痛或耳鸣。入院时,血液检查未发现正常尿检的疟原虫。抽取静脉血样本进行血液培养,然后进行经验性治疗,每天800 mg头孢曲松钠,静注125 mg stat的扑热息痛,然后每小时8小时开始125 mg。入院后第二天,患者在获得血液培养结果之前就死于败血性休克。总之,血液培养物的文化和生化鉴定显示出了C. violaceum感染。
更新日期:2019-11-19
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