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Obesity, transplantation, and bariatric surgery: An evolving solution for a growing epidemic.
American Journal of Transplantation ( IF 8.9 ) Pub Date : 2020-01-21 , DOI: 10.1111/ajt.15784
Tayyab S Diwan 1 , Tiffany C Lee 1 , Shunji Nagai 2 , Enrico Benedetti 3 , Andrew Posselt 4 , Ginny Bumgardner 5 , Sabrena Noria 5 , Bryan A Whitson 5 , Lloyd Ratner 6 , David Mason 7 , Jon Friedman 8 , Kenneth J Woodside 9 , Julie Heimbach 10
Affiliation  

The increasing obesity epidemic has major implications in the realm of transplantation. Patients with obesity face barriers in access to transplant and unique challenges in perioperative and postoperative outcomes. Because of comorbidities associated with obesity, along with the underlying end‐stage organ disease leading to transplant candidacy, these patients may not even be referred for transplant evaluation, much less be waitlisted or actually undergo transplant. However, the use of bariatric surgery in this population can help optimize the transplant candidacy of patients with obesity and end‐stage organ disease and improve perioperative and postoperative outcomes. We review the impact of obesity on kidney, liver, and cardiothoracic transplant candidates and recipients and explore potential interventions to address obesity in these populations.

中文翻译:

肥胖、移植和减肥手术:针对日益严重的流行病的不断发展的解决方案。

日益严重的肥胖流行病对移植领域具有重大影响。肥胖患者在获得移植方面面临障碍,在围手术期和术后结果方面面临独特的挑战。由于与肥胖相关的合并症,以及导致移植候选资格的潜在终末期器官疾病,这些患者甚至可能不会被转诊进行移植评估,更不用说等待或实际接受移植了。然而,在这一人群中使用减肥手术可以帮助优化肥胖和终末期器官疾病患者的移植候选资格,并改善围手术期和术后结果。我们回顾了肥胖对肾脏、肝脏和心胸移植候选者和接受者的影响,并探索解决这些人群肥胖问题的潜在干预措施。
更新日期:2020-01-21
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