Effects of Short-Peptide-Based Enteral Nutrition on the Intestinal Microcirculation and Mucosal Barrier in Mice with Severe Acute Pancreatitis.,Molecular Nutrition & Food Research

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Effects of Short-Peptide-Based Enteral Nutrition on the Intestinal Microcirculation and Mucosal Barrier in Mice with Severe Acute Pancreatitis.
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2020-01-29 , DOI: 10.1002/mnfr.201901191
Jian Zhang _{1,

2,

3} , Wen-Qiao Yu ₄ , Tao Wei _{1,

2,

3} , Cheng Zhang _{1,

2,

3} , Liang Wen _{1,

2,

3} , Qi Chen _{1,

2,

3} , Wei Chen _{1,

2,

3} , Jun-Yu Qiu _{1,

2,

3} , Yun Zhang _{1,

2,

3} , Ting-Bo Liang _{1,

2,

3}

Affiliation

Short‐peptide‐based enteral nutrition (SPEN) is absorbed more efficiently in patients with severe acute pancreatitis (SAP). More importantly, SPEN decreases SAP‐induced enterogenous infection risk. This study aims to investigate whether SPEN alleviates intestinal bacterial translocation in mice with SAP, and the underlying mechanisms.

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