In this study, low-density deep eutectic solvent combined with dispersive liquid-liquid microextraction was applied to the extraction of five benzoylurea insecticides (BUs, including diflubenzuron, triflumuron, hexaflumuron, flufenoxuron, and chlorfluazuron) from beverages. Then the extracted and concentrated samples were analyzed and detected using the high-performance liquid chromatography combined with an ultraviolet detector. The DESs were synthesized by [P14,6,6,6]Cl as hydrogen bond acceptor and tetradecyl alcohol as hydrogen bond donor, and then characterized by Fourier transform infrared spectroscopy. In the experiment, the key factors affecting the extraction efficiency were screened by Plackett-Burman design and optimized with the central composite design. The extraction recovery rates were 85.91-95.12%. The limits of detection and correlation coefficients of the method were 0.30-0.60 μg L-1 and 0.9992-0.9997. Finally, the method was applied to determine the BUs in four beverage samples, and satisfactory recoveries, within the range of 76.87-101.19% were achieved. The present method has the potential to be applied to the detection of BUs in aqueous samples.

中文翻译：

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使用深共熔溶剂从茶和果汁中提取苯甲酰脲农药。

在这项研究中，低密度的深共熔溶剂与分散液-液微萃取相结合，用于从饮料中提取五种苯甲酰脲类杀虫剂（BU，包括双氟苯磺隆，三氟磺隆，六氟磺隆，氟苯氧隆和氯氟脲隆）。然后使用高效液相色谱仪和紫外检测器结合对提取和浓缩的样品进行分析和检测。以[P14,6,6,6] Cl为氢键受体，十四烷醇为氢键供体合成了DES，然后通过傅里叶变换红外光谱进行了表征。在实验中，通过Plackett-Burman设计筛选了影响萃取效率的关键因素，并通过中央复合设计对其进行了优化。提取回收率为85.91-95.12％。该方法的检出限和相关系数分别为0.30-0.60μgL-1和0.9992-0.9997。最终，该方法用于测定四个饮料样品中的BU，回收率达到76.87-101.19％。本方法有可能应用于水样中BU的检测。