Abstract The potential of supramolecular solvents (SUPRAS) is investigated for the extraction of bioactive compounds from coffee cherry pulp, one of the major by-products generated in the coffee industry. SUPRAS made up of hexagonal inverted aggregates of octanoic acid in ethanol:water mixtures provided good extraction yields for bioactives (3.6 ± 0.3 mg caffeine g−1 and 0.9 ± 0.1 mg protocatechuic acid g−1) at a low solvent:sample ratio of 4:1 v/w and under mild operations conditions (5 min extraction at room temperature). SUPRAS-based extraction was optimized and extracts were analyzed to identify the main phenolic and alkaloid compounds. A variety of bioactives were present and extracts showed high antioxidant capacity by different assays (45% for DPPH and 91% for ABTS). Extraction efficiencies with SUPRAS were clearly superior than those obtained with organic solvents commonly used for valorization of coffee residues.

中文翻译：

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从咖啡果浆中提取生物活性物质的超分子溶剂

摘要 研究了超分子溶剂 (SUPRAS) 从咖啡果果肉中提取生物活性化合物的潜力，咖啡果果肉是咖啡工业中产生的主要副产品之一。SUPRAS 由乙醇：水混合物中辛酸的六角倒置聚集体组成，在低溶剂：样品比为 4 的情况下，为生物活性物质（3.6 ± 0.3 mg 咖啡因 g-1 和 0.9 ± 0.1 mg 原儿茶酸 g-1）提供了良好的提取率:1 v/w，在温和的操作条件下（室温提取 5 分钟）。对基于 SUPRAS 的提取进行了优化，并对提取物进行了分析，以确定主要的酚类和生物碱化合物。存在多种生物活性物质，提取物通过不同的测定显示出高抗氧化能力（DPPH 为 45%，ABTS 为 91%）。