Abstract A modified water-based freeze casting to fabricate long-range order lamellar Ti6Al4V scaffolds with macropores and high porosity has been developed by using the pre-frozen WS2 substrate as the template. Pores morphologies of the scaffolds relied on the previous ice crystal which had formed in templates and thus could be adjusted by altering the template structure. The decrease of gelatin in WS2 slurry transformed the bottom template from cell pore structure into the lamellar structure followed by improvement of lamellar orientation of the top Ti6Al4V scaffold. The pore widths of the scaffolds were in the range of 84–217 μm which were difficult to realize without the assisted template. The scaffolds also exhibited mechanical compatibility with bone tissues, indicating that the template-assisted freeze casting is a promising approach to fabricate macroporous Ti6Al4V implants.

中文翻译：

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具有长程有序层状结构的大孔 Ti6Al4V 支架的模板辅助冷冻铸造

摘要 以预冷冻的WS2基材为模板，研制了一种改性水基冷冻铸造法，制备具有大孔高孔隙率的长程有序层状Ti6Al4V支架。支架的孔隙形态依赖于先前在模板中形成的冰晶，因此可以通过改变模板结构来调整。WS2 浆液中明胶的减少使底部模板从细胞孔结构转变为层状结构，随后改善了顶部 Ti6Al4V 支架的层状取向。支架的孔隙宽度在 84-217 μm 的范围内，如果没有辅助模板很难实现。支架还表现出与骨组织的机械相容性，