当前位置: X-MOL 学术Small Methods › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Circadian Rhythm of Lipid Metabolism in Health and Disease
Small Methods ( IF 10.7 ) Pub Date : 2020-01-20 , DOI: 10.1002/smtd.201900601
Zhihui Zhang 1 , Haoran Xin 1 , Min‐Dian Li 1
Affiliation  

The circadian temporal organization of cellular functions segregates chemically incompatible processes into different times of the day. It is emerging that the molecular temporal organization of lipid metabolism throughout the day is crucial for physiological fitness, the dysfunction of which contributes to current epidemic metabolic diseases related to lipids. Here, current conceptual frameworks of the circadian clock system and knowledge of the circadian rhythm of lipid metabolism in different metabolic tissues and organs in health and disease are summarized. Recent advances in dietary and chemical approaches to modulate the circadian rhythm of lipids and the implications to treating human diseases are also reviewed.

中文翻译:

健康和疾病中脂质代谢的昼夜节律

细胞功能的昼夜节律组织将化学上不相容的过程分为一天中的不同时间。逐渐出现的是,全天脂质代谢的分子时间组织对于生理适应性至关重要,其功能障碍导致当前与脂质相关的流行性代谢疾病。在此,总结了生物钟系统的当前概念框架以及健康和疾病中不同代谢组织和器官中脂质代谢的生物钟节律知识。还综述了饮食和化学方法在调节脂质昼夜节律方面的最新进展及其对治疗人类疾病的影响。
更新日期:2020-01-20
down
wechat
bug