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Liver function test abnormalities in a longitudinal cohort of Thai individuals treated since acute HIV infection
Journal of the International AIDS Society ( IF 6 ) Pub Date : 2020-01-01 , DOI: 10.1002/jia2.25444
Michael J Peluso 1 , Donn J Colby 2, 3, 4 , Suteeraporn Pinyakorn 3, 4 , Sasiwimol Ubolyam 5 , Jintana Intasan 2 , Rapee Trichavaroj 6 , Nitiya Chomchey 2 , Peeriya Prueksakaew 2 , Bonnie M Slike 3, 4 , Shelly J Krebs 3, 4 , Ningbo Jian 3, 4 , Merlin L Robb 3, 4 , Praphan Phanuphak 5 , Nittaya Phanuphak 2 , Serena Spudich 7 , Jintanat Ananworanich 2, 3, 4, 8 , Eugène Kroon 2 ,
Affiliation  

Liver disease is a common cause of non‐AIDS morbidity and mortality in people living with HIV (PLHIV), but the prevalence and significance of liver function test (LFT) abnormalities in early HIV infection is unknown. This study aimed to characterize LFTs in a large cohort of participants with acute HIV infection initiating immediate antiretroviral therapy (ART) and examine the association between LFTs and biomarkers of HIV infection and inflammation.

中文翻译:

自急性 HIV 感染以来接受治疗的泰国纵向队列中的肝功能测试异常

肝病是 HIV 感染者 (PLHIV) 中非艾滋病发病率和死亡率的常见原因,但肝功能测试 (LFT) 异常在早期 HIV 感染中的患病率和意义尚不清楚。本研究旨在表征一大群急性 HIV 感染参与者开始立即抗逆转录病毒治疗 (ART) 的 LFT,并检查 LFT 与 HIV 感染和炎症的生物标志物之间的关联。
更新日期:2020-01-01
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