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A radical approach to diverse meroterpenoids.
Nature Chemistry ( IF 19.2 ) Pub Date : 2020-01-20 , DOI: 10.1038/s41557-019-0414-7
Andrew Gomm 1 , Adam Nelson 1
Affiliation  

Meroterpenoids are mixed terpenoid–polyketide natural products with a variety of biological activities. Now, a synthetic approach that combines biocatalytic oxidation with a range of other radical-based reactions enables the divergent synthesis of eight oxidized meroterpenoid natural products and one analogue.

中文翻译:

一种根本的方法来处理各种类萜。

类萜是混合的类萜-聚酮天然产物,具有多种生物活性。现在,将生物催化氧化与一系列其他基于自由基的反应相结合的合成方法,可以实现八种氧化的类金属萜天然产物和一种类似物的多样化合成。
更新日期:2020-01-21
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