The cover image created by Mariana Agostini de Moraes and colleagues, represents the self‐assembling of silk fibroin into globular structures within a continuous fibroin membrane matrix, encapsulating the drug model ‐ diclofenac sodium. These structures were only observed when the drug was incorporated in the fibroinsolution, prior to membrane preparation. The formation was spontaneous, and the globular structures presented regular size, shape and uniform distribution within the membrane. EDX mapping (red dots) of a fractured particle confirmed the high concentration of the drug within the globular structures. These results emphasize the potential use of silk fibroin for drug delivery applications. DOI: 10.1002/app.48763

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封面图片，第137卷，第16期

Mariana Agostini de Moraes及其同事创建的封面图像表示丝素蛋白在连续的丝素蛋白膜基质内自组装成球状结构，并封装了药物模型双氯芬酸钠。仅在膜制备之前将药物掺入纤维蛋白溶液中时才能观察到这些结构。形成是自发的，并且球状结构在膜内呈现规则的尺寸，形状和均匀分布。破裂颗粒的EDX映射（红色点）证实了球状结构内药物的高浓度。这些结果强调了丝素蛋白在药物递送应用中的潜在用途。DOI：10.1002 / app.48763