Recent Advances in the Construction of Phosphorus‐Substituted Heterocycles, 2009–2019,Advanced Synthesis & Catalysis

当前位置： X-MOL 学术 › Adv. Synth. Catal. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Recent Advances in the Construction of Phosphorus‐Substituted Heterocycles, 2009–2019
Advanced Synthesis & Catalysis ( IF 4.4 ) Pub Date : 2020-04-01 , DOI: 10.1002/adsc.201901540
Long Chen ₁ , Xiao‐Yan Liu ₁ , Yun‐Xiang Zou ₁

Affiliation

Phosphorus‐substituted heterocycles represent an important class of organophosphorus compounds, which not only widely exist in biologically active pharmaceuticals, agrochemicals, but also have widespread applications in material science and organic synthesis as ligands for transition metal complexes. The synthesis of such compounds integrates the development of new synthetic methods and exploration of efficient catalytic systems, reflects the latest achievements in organic, transition metal, photo and even electrochemical catalysis, and facilitates the synthesis of sufficient quantities of related compounds as potential medicinal agents and biological probes in this area. Over the past few decades, two major synthetic strategies have been established toward phosphorus‐substituted heterocycles. This review summarizes the recent progress in this field and discusses the reaction mechanisms in detail. The advantages and limitations of each subdivisional tactic are presented, and the synthetic opportunities still open are outlined.

中文翻译：

2009-2019年磷取代杂环的构建最新进展

磷取代的杂环代表一类重要的有机磷化合物，不仅作为生物活性药物，农用化学品广泛存在，而且作为过渡金属配合物的配体在材料科学和有机合成中也得到广泛应用。此类化合物的合成整合了新合成方法的开发和有效催化体系的探索，反映了有机，过渡金属，光催化甚至电化学催化方面的最新成就，并促进了足够数量的相关化合物作为潜在药物的合成。该领域的生物探针。在过去的几十年中，针对磷取代的杂环化合物已经建立了两种主要的合成策略。这篇综述总结了该领域的最新进展，并详细讨论了反应机理。提出了每种细分策略的优缺点，并概述了仍然开放的综合机会。

更新日期：2020-04-01

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11