Azo (‐N=N‐)‐ and imino (‐C=N‐)‐carboxylate triphenyltin(IV) compounds, which are well known for their promising biological activities, are usually synthesized by reacting a triphenyltin(IV) compound (oxide, hydroxide or chloride) with a suitably substituted carboxylic acid, under appropriate conditions. Their biological properties are influenced by the type/position of the functional azo or imino group in the carboxylate ligand skeleton. They are very effective in anticancer studies, being often better than the standard drug cisplatin in terms of cytotoxicity. A few of the azo‐appended carboxylate triphenyltin(IV) compounds also display anti‐bacterial, anti‐fungal and anti‐diabetic activities. The present manuscript highlights the syntheses, structures, and biological (i.e., anti‐cancer, anti‐bacterial, anti‐fungal and anti‐diabetic) activities of such triphenyltin(IV) compounds.

中文翻译：

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偶氮和氨基羧酸三苯基锡（IV）化合物的生物学评估

偶氮（-N = N-）和亚氨基（-C = N-）-羧化三苯基锡（IV）化合物，以其有前途的生物活性而闻名，通常是通过使三苯基锡（IV）化合物（氧化物，在适当的条件下，用适当取代的羧酸来取代氢氧化物或氢氧化物。它们的生物学特性受羧基配体骨架中功能偶氮或亚氨基基团的类型/位置的影响。它们在抗癌研究中非常有效，在细胞毒性方面通常优于标准药物顺铂。一些偶氮附加的羧酸三苯锡（IV）化合物也显示出抗菌，抗真菌和抗糖尿病活性。本手稿着重介绍了合成，结构和生物学特性（例如，抗癌，抗细菌，