Because of increasing demands for point-of-care chemo-/bio-sensor in analytical sciences, films-based sensing platforms experience a great upsurge. Electrospinning is recognized as a convenient, direct and powerful strategy to prepare nanofibrous films with typically networked structures, large surface area ratio, and high porosity. Recently, to obtain the highly sensitive, selective, and specific sensing nanofibrous films, creatively some functionalizing strategies such as the decoration or assembly of sensing elements and analytes-binding sites in electrospun NFs are explored. In this review, we summarized the recent advances in the functionalization of the electrospun NFs. Specifically, we systematically overview the chemo-/bio-sensing contributions of these exciting nanofibrous films by integrating the different output signals with abundant analytical objectives. Finally, we were thoroughly analyzed our fresh ideas of functionalized electrospun nanofibrous films and also presented some perspectives on the challenges and opportunities in chemo-/bio-sensing research.

由于分析科学中对即时医疗/化学/生物传感器的需求不断增长，基于胶片的传感平台经历了巨大的热潮。电纺丝被认为是制备具有典型网络结构，大表面积比和高孔隙率的纳米纤维膜的方便，直接和有效的策略。最近，为了获得高度敏感，选择性和特异的传感纳米纤维薄膜，创造性 地探索了一些功能化策略，例如电纺NF中传感元件和分析物结合位点的装饰或组装。在这篇综述中，我们总结了电纺NFs功能化的最新进展。具体来说，我们通过整合具有丰富分析目标的不同输出信号，系统地概述了这些令人兴奋的纳米纤维膜的化学/生物传感作用。最后，我们彻底分析了功能化电纺纳米纤维薄膜的新思想，并就化学/生物传感研究的挑战和机遇提出了一些看法。