BACKGROUND Malignant endometriosis in an episiotomy scar is rare; only seven cases have been reported previously. Here, we compare two cases of benign endometriosis and clear cell carcinoma. CASE PRESENTATION The first case was a 54-year-old woman who presented with a large perineal lesion in her episiotomy scar with high 18F-fluorodeoxyglucose uptake. This location had a history of endometriosis many years ago. She underwent radical excision of the mass and bilateral inguinal lymph node dissection. Histological and immunohistochemical analysis confirmed the presence of clear cell carcinoma arising from endometriosis. Assisted radiotherapy was performed after surgery due to a positive lymph node. No recurrence was detected over a 1-year follow-up period. The second case deals with a 3 × 2 cm mass in the episiotomy scar of a 33-year-old woman. Part of the anal sphincter was resected because of the close proximity of the lesion. Because the disease lay very close to the anus, she received anal sphincter reconstruction combined with mass excision. Pathology result showed typical endometrial glands and interstitial tissues. CONCLUSIONS Deleterious change only happens in patients experiencing perineal endometriosis. Complete excision is crucial for this form of disease; sometimes impairment of the anal sphincter is also necessary. Patients with malignancy required a combination of treatments in order to improve their prognosis.

中文翻译：

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透明膜癌和良性子宫内膜异位症在外阴切开术瘢痕中的比较-2例报告并文献复习。

背景技术在外阴切开术疤痕中恶性子宫内膜异位症很少见。以前只报告了七例。在这里，我们比较了良性子宫内膜异位症和透明细胞癌的两个案例。病例介绍第一例是一名54岁的女性，她的会阴切开术疤痕出现会阴部大病变，并摄取18 F-氟脱氧葡萄糖。这个位置有很多年前的子宫内膜异位病史。她接受了根治性肿块切除术和双侧腹股沟腹股沟淋巴结清扫术。组织学和免疫组织化学分析证实存在由子宫内膜异位引起的透明细胞癌。手术后由于淋巴结阳性而进行了辅助放疗。在1年的随访期内未发现复发。第二例涉及一名33岁妇女的癫痫切开瘢痕3×2厘米肿块。肛门括约肌部分切除，因为病变非常接近。因为该病非常靠近肛门，所以她接受了肛门括约肌再造和肿块切除术。病理结果显示典型的子宫内膜腺和间质组织。结论有害变化仅发生在会阴部子宫内膜异位症患者中。完全切除对于这种疾病至关重要。有时肛门括约肌受损也是必要的。恶性肿瘤患者需要联合治疗以改善其预后。病理结果显示典型的子宫内膜腺和间质组织。结论有害变化仅发生在会阴部子宫内膜异位症患者中。完全切除对于这种疾病至关重要。有时肛门括约肌受损也是必要的。恶性肿瘤患者需要联合治疗以改善其预后。病理结果显示典型的子宫内膜腺和间质组织。结论有害变化仅发生在会阴部子宫内膜异位症患者中。完全切除对于这种疾病至关重要。有时肛门括约肌受损也是必要的。恶性肿瘤患者需要联合治疗以改善其预后。