BACKGROUND This study aimed to assess whether urethral pain can be alleviated by urination in male patients undergoing flexible cystoscopy. METHODS Ninety-six male outpatients undergoing flexible cystoscopy were randomly divided into two groups. Patients in the test group urinated during flexible cystoscopy, whilst patients in the control group received no instructions to do so. All patients received 10 mL of 2% lidocaine gel prior to assessment. Using 0 (no-pain) to 10 (unbearable severe pain) pain scores (VAS), we assessed patient discomfort prior to anesthesia gel perfusion (baseline), during gel perfusion, during cystoscope insertion through the urethra, and 15 min post-examination analysis. The entire protocol was completed by a single doctor in our Department of Urology. RESULTS The groups showed no statistical differences regarding age or examination time. During cystoscope insertion, the test group recorded significantly lower pain scores 2 (IQR 1-3) - compared to the control group 3 (IQR 2-3), (P = 0.001). No significant differences between other evaluation points were observed between groups. CONCLUSION Urethral pain can be significantly alleviated by urination in male patients undergoing flexible cystoscopy through the urethra. TRIAL REGISTRATION Registry name: Clinical study of urination action to relieve urethral pain associated with flexible cystoscopy. Registration number: ChiCTR-INR-17013294 Date of Registration: 2017-11-08.

中文翻译：

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排尿对缓解与软性膀胱镜检查相关的男性尿道疼痛的功效：一项单中心随机试验。


背景本研究旨在评估接受软性膀胱镜检查的男性患者是否可以通过排尿缓解尿道疼痛。方法将96例接受软性膀胱镜检查的男性门诊患者随机分为两组。测试组患者在柔性膀胱镜检查期间小便，而对照组患者没有收到这样做的指示。所有患者在评估前均接受 10 mL 2% 利多卡因凝胶。我们使用 0（无痛）至 10（难以忍受的剧烈疼痛）疼痛评分 (VAS) 评估患者在麻醉凝胶灌注前（基线）、凝胶灌注期间、膀胱镜通过尿道插入期间以及检查后 15 分钟的不适情况分析。整个方案由我们泌尿外科的一名医生完成。结果 各组在年龄或检查时间方面没有显着差异。在膀胱镜插入期间，测试组记录的疼痛评分 2 (IQR 1-3) 显着低于对照组 3 (IQR 2-3)，(P = 0.001)。组间其他评价点之间没有观察到显着差异。结论 男性患者经尿道进行膀胱软镜检查后排尿可明显减轻尿道疼痛。试验注册 注册名称：排尿作用缓解与软性膀胱镜检查相关的尿道疼痛的临床研究。注册号：ChiCTR-INR-17013294 注册日期：2017-11-08。