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Fecal microbiota transplantation in disease therapy.
Clinica Chimica Acta ( IF 3.2 ) Pub Date : 2020-01-20 , DOI: 10.1016/j.cca.2019.12.010
Hanna Antushevich 1
Affiliation  

Fecal microbiota transplantation (FMT) is the introduction (transplantation) of gut microbiota obtained from the faeces of a healthy donor into the patient's gastrointestinal tract. Most often, such therapy is used the treatment of gastrointestinal diseases caused by the activity of pathogenic or conditionally pathogenic microorganisms, however, recently an increasing number of studies have reported the use of fecal microbiota transplantation for the treatment of diseases such as metabolic syndrome, diabetes, cancer and Parkinson's disease. This review article presents the results of studies concerning the impact of FMT on weight gain, immunological response and the treatment of neurological and gastrointestinal diseases and cancer. The procedure of fecal microbiota transplantation and possible side effects that may appear in FMT recipients are also described.

中文翻译:

粪便菌群移植在疾病治疗中的应用。

粪便微生物菌群移植(FMT)是从健康供体的粪便中获得的肠道菌群导入(移植)到患者的胃肠道中。大多数情况下,这种疗法用于治疗由致病性或条件致病性微生物的活动引起的胃肠道疾病,但是,最近越来越多的研究报告了将粪便微生物群移植用于治疗诸如代谢综合征,糖尿病等疾病,癌症和帕金森氏病。这篇综述文章介绍了有关FMT对体重增加,免疫反应以及神经,胃肠道疾病和癌症治疗的影响的研究结果。
更新日期:2020-01-21
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