Abstract In this study, the removal of tetracycline from aqueous solutions with chitosan obtained from mussel shells was optimized and investigated using responce surface methodology. For this aim, the central composite design was used to optimize the four variable factors (sorbent dosage (0.4–1.0 g), time (20−60 min), temparature (10−30 °C) and initial TC concentration (50−100 mg/L)) for the removal of TC from aqueous solutions by chitosan obtained from mussel shells. According to the RSM analysis results, optimum conditions for maximum TC removal efficiency were determined as 90.5 mg/L for initial TC concentration, 35.9 min for time, 29.9 °C for temperature and 0.4 g for sorbent dosage. It was observed that the tetracycline was crystallized on mussel shells. According to the results of XRD after adsorption, the content of mussel shells were observed as 60% calcite, 5.6% overite, 9.4% aragonite and calcium hydroxide 25%, respectively. As a result, experiments showed that chitosan obtained from mussel shells were a good adsorbant for tetracycline removal from aqueous solutions.

中文翻译：

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使用 RSM 优化从贻贝壳中获得的壳聚糖去除四环素

摘要 在这项研究中，使用响应表面法优化和研究了从贻贝壳中提取的壳聚糖从水溶液中去除四环素的方法。为此，中心复合设计用于优化四个可变因素（吸附剂剂量（0.4-1.0 g）、时间（20-60 分钟）、温度（10-30 °C）和初始 TC 浓度（50-100 mg/L)) 用于通过从贻贝壳中获得的壳聚糖从水溶液中去除 TC。根据 RSM 分析结果，最大 TC 去除效率的最佳条件确定为初始 TC 浓度为 90.5 mg/L，时间为 35.9 min，温度为 29.9 °C，吸附剂用量为 0.4 g。观察到四环素在贻贝壳上结晶。根据吸附后的XRD结果，观察到贻贝壳的含量分别为 60% 方解石、5.6% 白云石、9.4% 文石和 25% 氢氧化钙。结果，实验表明从贻贝壳中提取的壳聚糖是去除水溶液中四环素的良好吸附剂。