OBJECTIVES To evaluate the effect of various titanium abutment modifications on the behaviour of peri-implant soft tissue healing, inflammation and maintenance. MATERIAL AND METHODS An electronic database research until 30 April 2019 was performed. A meta-analysis (MA) for each outcome parameter was performed by using the random-effects models with the DerSimonian-Laird estimator. RESULTS Ten studies were included in the present review. Four studies with a long follow-up (5-6 years) reported the outcomes in a heterogeneous way and were suitable for MA. Six studies (4 RCT, 2 CCT) including 118 patients and 182 implants dealing with a modified healing abutment surface and short follow-up were selected for MA. The MA for PI and BoP as outcome showed no significant differences between surfaces (PI: P = 0.091; BoP: P = 0.099). The MA for PD as outcome showed no significant differences between surfaces (P = 0.488). No statistical significance was found by evaluating each mixed-effects model for potential moderators (type of study, study design, number of implants, follow-up length). The other four studies with a longer follow-up (5-6 years) reported contradictory results depending on the surface treatment investigated. CONCLUSIONS Within their limits, the present findings suggest that peri-implant soft tissue may not be affected by the surface treatment of titanium abutments on the short term. Contrasting results are reported in longer follow-up periods depending on the technique used to modify the abutment. CLINICAL RELEVANCE Clinicians should carefully evaluate the use of a modified titanium surface in their practice. Even if no differences in terms of inflammation are present at short term, these findings need to be validated in long-term studies.

中文翻译：

---

钛基台表面改性和种植体周围组织行为：系统评价和荟萃分析。

目的评估各种钛基台修饰对种植体周围软组织愈合，炎症和维持行为的影响。材料与方法进行了电子数据库研究，直至2019年4月30日。通过使用具有DerSimonian-Laird估计量的随机效应模型对每个结果参数进行荟萃分析（MA）。结果本综述包括十项研究。四个长期随访（5-6年）的研究以不同的方式报告了结局，并且适合于MA。选择了6项研究（4篇RCT，2篇CCT），包括118例患者和182枚植入物，这些植入物处理了改良的愈合基台表面并进行了短期随访。PI和BoP作为结果的MA在表面之间无显着差异（PI：P = 0.091； BoP：P = 0.099）。PD作为结果的MA显示表面之间无显着差异（P = 0.488）。通过评估每个混合效应模型的潜在主持人（研究类型，研究设计，植入物数量，随访时间），未发现统计学意义。其他四项随访时间较长（5-6年）的研究报告了相矛盾的结果，具体取决于所研究的表面处理。结论本研究结果在其范围内，短期内钛基牙的表面处理可能不会影响种植体周围软组织。在更长的随访期内报告了不同的结果，具体取决于用于修改基台的技术。临床相关性临床医师应在实践中仔细评估改性钛表面的使用。