Metabolic profiling of organic acids in honey by stable isotope labeling assisted liquid chromatography-mass spectrometry,Journal of Food Composition and Analysis

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Metabolic profiling of organic acids in honey by stable isotope labeling assisted liquid chromatography-mass spectrometry
Journal of Food Composition and Analysis ( IF 4.0 ) Pub Date : 2020-04-01 , DOI: 10.1016/j.jfca.2020.103423
Na An , Wen-Jing Cai , Quan-Fei Zhu , Wei Wang , Dilshad Hussain , Yu-Qi Feng

Abstract Organic acids in honey have great nutritive and medicinal value such as antimicrobial and antioxidant activities. In this study, profiling of organic acids in honey is carried out by sequential liquid-liquid extraction assisted isotope labeling-liquid chromatography-mass spectrometry. A total of 493 potential organic acids are detected in honey, and 165 of those are confirmed by comparing with authentic standards and interpretation of obtained MSn spectra. Findings from this study further expand our understanding about the number of organic acids in honey, increasing from 120 (previously reported) to 258. Moreover, we find that the composition of organic acids detected in rape, acacia and Chinese astragalus honey is quite similar; but their contents show certain variations. This study provides basic knowledge about the number and nature of organic acids in honey and could be stepping stone to explore the link between organic acids and nutritional and medicinal characteristics of honey.

更新日期：2020-04-01

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