Herein, a novel nitrogen-doped carbon quantum dots (N-CQDs) with bright blue fluorescence were prepared using glycine and urea by a facile solid-heat method. The prepared N-CQDs had a relatively high quantum yield (QY = 21.04 %), excellent photobleaching resistance, acid and alkali resistance. Moreover, it was used as fluorescent probe for the detection of dopamine (DA) with high selectivity and a low limit of detection (LOD = 0.0972 μM). Additionally, this fluorescent probe was successfully used to the determination of DA in human serum and rat serum with satisfactory recoveries (98.24 %–107.86 %), indicating this probe is was a promising biomolecular sensor for quantitation of DA in serum.

本文中，通过甘氨酸和尿素通过简便的固热方法制备了具有亮蓝色荧光的新型氮掺杂碳量子点（N-CQDs）。制备的N-CQD具有相对较高的量子产率（QY ＝ 21.04％），优异的耐光漂白性，耐酸碱性。此外，它被用作荧光探针，以高选择性和低检测限（LOD = 0.0972μM）检测多巴胺（DA）。此外，该荧光探针已成功用于测定人血清和大鼠血清中的DA，回收率令人满意（98.24％–107.86％），表明该探针是用于定量血清DA的有前途的生物分子传感器。