A simple construction for various 2,4-disubstituted thiazoles via palladium(II)-catalyzed C(sp)–C(sp²) and C-N cascade coupling reactions was developed. Various substrates can be tolerated with good yields. And its ligand-free condition demonstrates the practicability of this method.

中文翻译：

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通过无配体的钯（II）催化的C（sp）–C（sp ²）偶联反应与2,4-二取代的噻唑的级联反应

通过钯（II）催化的C（sp）–C（sp ²）和CN级联偶联反应，开发了各种2,4-二取代噻唑的简单结构。可以耐受各种底物，且产率高。并且其无配体条件证明了该方法的实用性。