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A Catheter-Deployable Soft Robotic Inflatable Basket for Enhanced Conformability to the Left Atrium of the Heart.
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2020-01-16 , DOI: 10.1002/adhm.201900951 Nazanin Farokhnia 1 , Alexandre Caprio 1 , Varun Kashyap 1 , Subhi Al'Aref 1 , Lohendran Baskaran 1 , Bobak Mosadegh 1 , Simon Dunham 1
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2020-01-16 , DOI: 10.1002/adhm.201900951 Nazanin Farokhnia 1 , Alexandre Caprio 1 , Varun Kashyap 1 , Subhi Al'Aref 1 , Lohendran Baskaran 1 , Bobak Mosadegh 1 , Simon Dunham 1
Affiliation
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This paper presents the design, fabrication, and test results for a novel basket catheter that utilizes soft robotic technology, which can conform to complex patient anatomy. Two designs of basket-shaped balloons in three sizes are fabricated based on a CO2 laser cutting method from thin (<50 µm) thermoplastic polyurethane. The balloons are deployed in four soft-material 3D printed left atria, whose geometries are based on volume rendered segmentation of cardiac computed tomography (CT) scans. The coverage and conformability to the realistic patient anatomies is tracked with the small patches of pH paper that indicate, via a color change, contact with a basic solution that lined the 3D printed atriums. The conformability of these inflatable basket catheters is demonstrated as high as (85%) for the optimized design. To visualize the balloon's performance, microCT images of balloons deployed in 3D printed models are shown. These images show the ability of the balloons to adapt to complex patient anatomy and do not exhibit any spline bunching or other deleterious mechanical behavior. This platform has the potential to be coupled with electrical sensors for simultaneous multisensor mapping of atrial fibrillation and other cardiac arrhythmias.
中文翻译：
导管可部署的软机器人充气篮，可增强对心脏左心房的适应性。
本文介绍了利用软机器人技术的新型篮式导管的设计，制造和测试结果，该技术可以适应复杂的患者解剖结构。基于CO2激光切割方法，从薄的（<50 µm）热塑性聚氨酯中制造出两种设计的三种尺寸的篮形气球。气球被部署在四个软材料3D打印的左心房中，其几何形状基于心脏计算机断层扫描（CT）扫描的体积渲染分割。用一小片pH纸跟踪与实际患者解剖结构的覆盖范围和贴合性，这些小纸片通过颜色变化指示与衬有3D打印中庭的基本溶液接触。这些充气篮式导管的优化设计具有高达（85％）的一致性。可视化气球' 的性能，显示了部署在3D打印模型中的气球的microCT图像。这些图像显示了气球适应复杂的患者解剖结构的能力，并且没有表现出任何花键聚集或其他有害的机械行为。该平台具有与电传感器耦合的潜力，可同时对心房颤动和其他心律不齐进行多传感器定位。
更新日期：2020-02-19
中文翻译：
导管可部署的软机器人充气篮，可增强对心脏左心房的适应性。
本文介绍了利用软机器人技术的新型篮式导管的设计，制造和测试结果，该技术可以适应复杂的患者解剖结构。基于CO2激光切割方法，从薄的（<50 µm）热塑性聚氨酯中制造出两种设计的三种尺寸的篮形气球。气球被部署在四个软材料3D打印的左心房中，其几何形状基于心脏计算机断层扫描（CT）扫描的体积渲染分割。用一小片pH纸跟踪与实际患者解剖结构的覆盖范围和贴合性，这些小纸片通过颜色变化指示与衬有3D打印中庭的基本溶液接触。这些充气篮式导管的优化设计具有高达（85％）的一致性。可视化气球' 的性能，显示了部署在3D打印模型中的气球的microCT图像。这些图像显示了气球适应复杂的患者解剖结构的能力，并且没有表现出任何花键聚集或其他有害的机械行为。该平台具有与电传感器耦合的潜力，可同时对心房颤动和其他心律不齐进行多传感器定位。
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