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Plasma Phospholipids with Long-Chain Polyunsaturated Fatty Acids and Dihydroceramides at the Crossroads of Iron Stores and Insulin Resistance.
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2020-01-23 , DOI: 10.1002/mnfr.201901055
Jordi Mayneris-Perxachs 1 , Aya Mousa 2 , Negar Naderpoor 2 , José-Manuel Fernández-Real 1 , Barbora de Courten 2
Affiliation  

Iron plays an important role in the pathogenesis of insulin resistance (IR) and type 2 diabetes. Recent studies suggest a role of specific lipids in the induction of IR, but the potential relationships between iron and lipid metabolites in relation to IR have not been explored. Therefore, the aim of the study is to evaluate the association among iron, IR, and the lipidome.

中文翻译:

具有长链多不饱和脂肪酸和二氢神经酰胺的血浆磷脂在铁储存和胰岛素抵抗的十字路口。

铁在胰岛素抵抗 (IR) 和 2 型糖尿病的发病机制中起着重要作用。最近的研究表明特定脂质在 IR 诱导中的作用,但尚未探索铁和脂质代谢物与 IR 之间的潜在关系。因此,该研究的目的是评估铁、IR 和脂质组之间的关联。
更新日期:2020-01-23
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