In 1968 Burkholder and associates (J. Antibiot. (Tokyo) 1968, 21, 659–664) isolated the antifungal toxin goniodomin from an unidentified Puerto Rican dinoflagellate and partially characterized its structure. Subsequently, a metabolite of Alexandrium hiranoi was isolated by Murakami et al. from a bloom in Japan and its structure was established (Tetrahedron Lett. 1988, 29, 1149–1152). The Japanese substance had strong similarities to Burkholder's but due to uncertainty as to whether it was identical or only similar, Murakami named his toxin goniodomin A. A detailed study of this question now provides compelling evidence that Burkholder's goniodomin is identical to goniodomin A. Morphological characterization of the dinoflagellate suggests that it was the genus Alexandrium but insufficient evidence is available to make a definite identification of the species. This is the only report of goniodomin in the Caribbean region.

在1968年伯克霍尔德和同事（J.抗菌素。（东京） 1968年，21，659-664）从一个不明波多黎各甲藻中分离抗真菌毒素goniodomin和部分特征在于它的结构。随后，Murakami等人分离了山茱Alexandr的代谢产物。从在日本和其结构的开花成立（四面体通讯。 1988年，29，1149–1152）。日本物质与Burkholder的强相似性，但由于不确定其是否相同，村上隆将其命名为毒素GoniodominA。对该问题的详细研究现在提供了令人信服的证据，证明Burkholder的Goniodomin与Goniodomin A完全相同。甲鞭毛藻的研究表明它是亚历山大藻属，但没有足够的证据可以明确地鉴定该物种。这是加勒比地区淋巴菌素的唯一报道。