Aryl 2,2,2-trifluoroethyl sulfides were synthesized by copper(I)-catalyzed nucleophilic aromatic substitution reaction (Ullmann coupling). The method requires aryl iodides and 2,2,2-trifluoroethyl thioacetate as starting materials, benzylamine as solvent and base, and a copper(I) bromide as a catalyst. The reaction mixture was stirred at 110 °C for 6 h under inert atmosphere to afford the targeted aryl 2,2,2-trifluoroethyl sulfides in moderate to good yield.

中文翻译：

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芳基2,2,2-三氟乙基硫醚的合成

通过铜（I）催化的亲核芳族取代反应（Ullmann偶联）合成了芳基2,2,2-三氟乙基硫化物。该方法需要芳基碘化物和2,2,2-三氟乙基硫代乙酸酯作为起始原料，苄胺作为溶剂和碱，以及溴化铜（I）作为催化剂。将反应混合物在惰性气氛下在110℃搅拌6h，以中等至良好的产率得到目标芳基2,2,2-三氟乙基硫醚。