Nowadays, the development of various biosensors as a new generation of analytical instruments is one of the most promising research fields of analytical biology. Among all types of biosensors, enzyme based biosensors have an interesting property, the inherent inhibition phenomena given the enzyme-substrate complex formation. Over the past years, electrochemical enzyme based biosensors have emerged as simple, rapid and ultra-sensitive devices for determination or detection of different compounds in the drugs and food samples. In this review, general views to enzymes related with their history, classification, immobilization, and inhibition information is presented to researchers. Then, a detailed description is provided for enzyme based and electrochemical enzyme based biosensors. Finally, some selected electrochemical enzyme based biosensor studies developed for food and drug analysis are summarized and tabulated.

如今，作为新一代分析仪器的各种生物传感器的开发是分析生物学最有前途的研究领域之一。在所有类型的生物传感器中，基于酶的生物传感器具有令人感兴趣的特性，即固有的抑制现象在形成酶-底物复合物后形成。在过去的几年中，基于电化学酶的生物传感器已经成为用于确定或检测药物和食品样品中不同化合物的简单，快速和超灵敏的设备。在这篇综述中，向酶介绍了与酶的历史，分类，固定化和抑制信息有关的一般观点。然后，提供了对基于酶和基于电化学酶的生物传感器的详细描述。最后，