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Electrophysiological dynamics of antagonistic brain networks reflect attentional fluctuations.
Nature Communications ( IF 14.7 ) Pub Date : 2020-01-16 , DOI: 10.1038/s41467-019-14166-2
Aaron Kucyi 1 , Amy Daitch 1 , Omri Raccah 1 , Baotian Zhao 2, 3 , Chao Zhang 2, 3 , Michael Esterman 4, 5 , Michael Zeineh 6 , Casey H Halpern 7 , Kai Zhang 2, 3 , Jianguo Zhang 2, 3 , Josef Parvizi 1
Affiliation  

Neuroimaging evidence suggests that the default mode network (DMN) exhibits antagonistic activity with dorsal attention (DAN) and salience (SN) networks. Here we use human intracranial electroencephalography to investigate the behavioral relevance of fine-grained dynamics within and between these networks. The three networks show dissociable profiles of task-evoked electrophysiological activity, best captured in the high-frequency broadband (HFB; 70-170 Hz) range. On the order of hundreds of milliseconds, HFB responses peak fastest in the DAN, at intermediate speed in the SN, and slowest in the DMN. Lapses of attention (behavioral errors) are marked by distinguishable patterns of both pre- and post-stimulus HFB activity within each network. Moreover, the magnitude of temporally lagged, negative HFB coupling between the DAN and DMN (but not SN and DMN) is associated with greater sustained attention performance and is reduced during wakeful rest. These findings underscore the behavioral relevance of temporally delayed coordination between antagonistic brain networks.

中文翻译:

拮抗性大脑网络的电生理动力学反映了注意力波动。

神经影像学证据表明,默认模式网络(DMN)表现出具有背侧注意力(DAN)和显着性(SN)网络的拮抗活性。在这里,我们使用人类颅内脑电图研究这些网络内部和之间的细粒度动力学的行为相关性。这三个网络显示了任务诱发的电生理活动的可分离曲线,最好在高频宽带(HFB; 70-170 Hz)范围内捕获。大约在数百毫秒内,HFB响应在DAN中达到峰值最快,在SN中处于中等速度,而在DMN中最慢。每个网络中刺激前和刺激后HFB活动的可区分模式标志着注意力的流逝(行为错误)。而且,时间上的滞后性 DAN和DMN(而不是SN和DMN)之间的负HFB耦合具有更高的持续注意力表现,并在清醒休息时减少。这些发现强调了拮抗性脑网络之间暂时延迟协调的行为相关性。
更新日期:2020-01-16
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