BACKGROUND Gastrointestinal cancer is one of the most common malignancies and imposes heavy burdens on both individual health and social economy. We sought to survey the effect of a self-care education program on quality of life and fatigue in gastrointestinal cancer patients who received chemotherapy. METHODS Ninety-one eligible gastrointestinal cancer patients were enrolled in this study and 86 valid samples were analyzed. Data were acquired with a demographics questionnaire, endpoint multidimensional questionnaire and the European Organization for Research and Treatment of Cancer (EORTC) quality of life questionnaire QLQ-C30. The collected data were analyzed using SPSS software. RESULTS The self-care education intervention significantly improved the quality of life with respect to emotional function (p = 0.018), role function (p = 0.041), cognitive function (p = 0.038) and alleviated side effects such as nausea/vomiting (p = 0.028) and fatigue (p = 0.029). Further analysis demonstrated that the self-care education benefited total fatigue, affective fatigue and cognitive fatigue in gastrointestinal cancer patients regardless of baseline depression. CONCLUSION Our results suggested the beneficial effects of the self-care education in both quality of life and anti-fatigue in gastrointestinal cancer patients under chemotherapy. The self-care education could be considered as a complementary approach during combination chemotherapy in gastrointestinal cancer patients.

中文翻译：

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附加自我保健教育对接受化疗的胃肠道癌症患者的生活质量和疲劳的影响。

背景技术胃肠道癌是最常见的恶性肿瘤之一，并且给个人健康和社会经济带来沉重负担。我们试图调查一项自我护理教育计划对接受化疗的胃肠道癌症患者生活质量和疲劳的影响。方法纳入本研究的91例胃肠道癌患者，并分析86份有效样本。数据通过人口统计学问卷，终点多维问卷和欧洲癌症研究与治疗组织（EORTC）生活质量问卷QLQ-C30获得。使用SPSS软件分析收集的数据。结果自我护理教育干预显着改善了情绪功能（p = 0.018），角色功能（p = 0.041），生活质量。认知功能（p = 0.038）和减轻的副作用，例如恶心/呕吐（p = 0.028）和疲劳（p = 0.029）。进一步的分析表明，无论基线抑郁症如何，自我护理教育都可以使胃肠道癌患者的总疲劳，情感疲劳和认知疲劳受益。结论我们的研究结果表明，自我护理教育对接受化疗的胃肠道癌症患者的生活质量和抗疲劳能力均具有有益的作用。自我护理教育可以被视为胃肠道癌患者联合化疗期间的一种补充方法。胃肠道肿瘤患者的情感疲劳和认知疲劳，与基线抑郁无关。结论我们的研究结果表明，自我护理教育对接受化疗的胃肠道癌症患者的生活质量和抗疲劳能力均具有有益的作用。自我护理教育可以被视为胃肠道癌患者联合化疗期间的一种补充方法。胃肠道肿瘤患者的情感疲劳和认知疲劳，与基线抑郁无关。结论我们的研究结果表明，自我护理教育对接受化疗的胃肠道癌症患者的生活质量和抗疲劳能力均具有有益的作用。自我护理教育可以被视为胃肠道癌患者联合化疗期间的一种补充方法。