Race-specific differences in the phase coherence between blood flow and oxygenation: A simultaneous NIRS, white light spectroscopy and LDF study.,Journal of Biophotonics

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Race-specific differences in the phase coherence between blood flow and oxygenation: A simultaneous NIRS, white light spectroscopy and LDF study.
Journal of Biophotonics ( IF 2.0 ) Pub Date : 2020-02-03 , DOI: 10.1002/jbio.201960131
Yunus A Abdulhameed _{1,

2} , Peter V E McClintock ₁ , Aneta Stefanovska ₁

Affiliation

Race‐specific differences in the level of glycated hemoglobin are well known. However, these differences were detected by invasive measurement of mean oxygenation, and their understanding remains far from complete. Given that oxygen is delivered to the cells by hemoglobin through the cardiovascular system, a possible approach is to investigate the phase coherence between blood flow and oxygen transportation. Here we introduce a noninvasive optical method based on simultaneous recordings using NIRS, white light spectroscopy and LDF, combined with wavelet‐based phase coherence analysis. Signals were recorded simultaneously for individuals in two groups of healthy subjects, 16 from Sub‐Saharan Africa (BA group) and 16 Europeans (CA group). It was found that the power of myogenic oscillations in oxygenated and de‐oxygenated hemoglobin is higher in the BA group, but that the phase coherence between blood flow and oxygen saturation, or blood flow and hemoglobin concentrations is higher in the CA group

中文翻译：

血流和氧合之间相位相干性的种族特异性差异：同时进行 NIRS、白光光谱和 LDF 研究。

糖化血红蛋白水平的种族特异性差异是众所周知的。然而，这些差异是通过平均氧合的侵入性测量来检测的，并且它们的理解还远未完成。鉴于血红蛋白通过心血管系统将氧气输送到细胞，一种可能的方法是研究血流和氧气运输之间的相位相干性。在这里，我们介绍了一种基于使用 NIRS、白光光谱和 LDF 同时记录的无创光学方法，并结合基于小波的相位相干分析。同时记录两组健康受试者的信号，其中 16 名来自撒哈拉以南非洲（BA 组）和 16 名欧洲人（CA 组）。

更新日期：2020-02-03

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