Key Considerations for Accurate Exposures in Ecotoxicological Assessments of Perfluorinated Carboxylates and Sulfonates,Environmental Toxicology and Chemistry

当前位置： X-MOL 学术 › Environ. Toxicol. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Key Considerations for Accurate Exposures in Ecotoxicological Assessments of Perfluorinated Carboxylates and Sulfonates
Environmental Toxicology and Chemistry ( IF 3.6 ) Pub Date : 2020-01-15 , DOI: 10.1002/etc.4667
Justin N Rewerts ₁ , Emerson C Christie ₂ , Alix E Robel ₂ , Todd A Anderson ₃ , Christopher McCarthy ₄ , Christopher J Salice ₅ , Jennifer A Field _{1,

2}

Affiliation

Toxicity reference values for per‐ and polyfluoroalkyl substances (PFAS) vary even when the same test organism is studied. Although the need to confirm dosing solution concentrations is widely accepted, there are no experimental data to inform best practices when PFAS solutions are prepared. Laboratory data indicate that dissolution time of PFAS solids causes statistically significant deviations between nominal and measured concentrations. Mixing times for select PFAS varied between 2 and 5 h, depending on carbon fluorine chain‐length. Environ Toxicol Chem 2021;40:677–688. © 2020 SETAC

中文翻译：

全氟羧酸盐和磺酸盐生态毒理学评估中准确暴露的关键考虑因素

即使在研究相同的测试生物时，全氟烷基物质和多氟烷基物质 (PFAS) 的毒性参考值也会有所不同。尽管确认给药溶液浓度的需要已被广泛接受，但在制备 PFAS 溶液时，没有实验数据来告知最佳实践。实验室数据表明，PFAS 固体的溶解时间会导致标称浓度和测量浓度之间存在统计学上的显着偏差。特定 PFAS 的混合时间在 2 到 5 小时之间变化，具体取决于碳氟链长度。环境毒理学化学2021；40：677-688。© 2020 SETAC

更新日期：2020-01-15

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11