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Stereoselective Bioreduction of Telluro‐Acetophenones to Optically Active Hydroxy Tellurides
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2020-02-19 , DOI: 10.1002/ejoc.201901841
Pamela Taisline Bandeira 1, 2 , Vicente Gotor-Fernández 2 , Leandro Piovan 1
Affiliation  

A series of telluro‐acetophenones has been chemically synthesized and later reduced using alcohol dehydrogenases of complementary selectivity. Therefore, (R) and (S)‐hydroxy tellurides have been obtained in good to excellent optical purities under mild reaction conditions in aqueous medium.
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中文翻译:

碲-乙酰苯的立体选择性生物还原成光学活性羟基碲化物

化学合成了一系列碲-乙酰苯,后来使用具有互补选择性的醇脱氢酶将其还原。因此,在水性介质中,在温和的反应条件下,可以获得(R)和(S)-羟基碲化物,具有良好的光学纯度。
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更新日期:2020-02-19
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