Abstract The resistance of bacteria toward antibacterial drugs is a rising problem. This threat is a major concern for space stations, where antibacterial surfaces would be ideal for materials which also need to be corrosion-resistant, hard and durable. Accordingly, the purpose of this work is to investigate novel coatings that have superhydrophobic mushroom microstructures. The microstructures are made of nickel deposited on a substrate which is composed of a gold layer on top of the silicon. The microstructures were fabricated with UV-light assisted nanoimprint lithography. These superhydrophobic microstructures have a well-defined alignment and shape which does not have any detrimental effect on the plastic deformation of the substrate. Similar structures were coated with carbon by hot-filament chemical vapour deposition (HFCVD) for a duration varying from 30 min to 120 min. Raman spectroscopy shows that the coating is composed of graphite, due to nickel-induced graphitisation during the deposition process. The antibacterial evaluation shows the bare nickel microstructures offer no antibacterial properties despite their superhydrophobic behaviour. On the other hand, the graphitic coated microstructures demonstrate significant antibacterial properties. Especially, 30 min HFCVD coated samples was antibacterial against E. coli and S. aureus with Gram-dependence and dependent on the coating deposition duration.

中文翻译：

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由蘑菇形微结构和 HFCVD 石墨组成的新型涂层的表征和抗菌研究

摘要 细菌对抗菌药物的耐药性是一个日益严重的问题。这种威胁是空间站的一个主要问题，其中抗菌表面对于还需要耐腐蚀、坚硬和耐用的材料来说是理想的选择。因此，这项工作的目的是研究具有超疏水蘑菇微观结构的新型涂层。微结构由沉积在基板上的镍制成，该基板由硅顶部的金层组成。微结构是用紫外光辅助纳米压印光刻制造的。这些超疏水微结构具有明确的排列和形状，对基材的塑性变形没有任何不利影响。类似的结构通过热丝化学气相沉积 (HFCVD) 涂覆碳，持续时间从 30 分钟到 120 分钟不等。拉曼光谱表明，由于沉积过程中镍诱导的石墨化，涂层由石墨组成。抗菌评估表明，尽管具有超疏水行为，但裸镍微结构不提供抗菌性能。另一方面，石墨涂层的微结构表现出显着的抗菌性能。特别是，30 分钟的 HFCVD 涂层样品对大肠杆菌和金黄色葡萄球菌具有抗菌作用，具有革兰氏依赖性并取决于涂层沉积持续时间。抗菌评估表明，尽管具有超疏水行为，但裸镍微结构不提供抗菌性能。另一方面，石墨涂层的微结构表现出显着的抗菌性能。特别是，30 分钟的 HFCVD 涂层样品对大肠杆菌和金黄色葡萄球菌具有抗菌作用，具有革兰氏依赖性并取决于涂层沉积持续时间。抗菌评估表明，尽管具有超疏水行为，但裸镍微结构不提供抗菌性能。另一方面，石墨涂层的微结构表现出显着的抗菌性能。特别是，30 分钟的 HFCVD 涂层样品对大肠杆菌和金黄色葡萄球菌具有抗菌作用，具有革兰氏依赖性并取决于涂层沉积持续时间。