Synergic effect of doxorubicin release and two-photon irradiation of Mn2+-doped Prussian blue nanoparticles on cancer therapy,RSC Advances

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Synergic effect of doxorubicin release and two-photon irradiation of Mn2+-doped Prussian blue nanoparticles on cancer therapy
RSC Advances ( IF 3.9 ) Pub Date : 2020-1-15 , DOI: 10.1039/c9ra09133e
Lamiaa M A Ali _{1,

2} , Emna Mathlouthi _{3,

4} , Maëlle Cahu ₃ , Saad Sene ₃ , Morgane Daurat _{1,

5} , Jérôme Long ₃ , Yannick Guari ₃ , Fabrice Salles ₃ , Joël Chopineau ₃ , Jean-Marie Devoisselle ₃ , Joulia Larionova ₃ , Magali Gary-Bobo ₁

Affiliation

We demonstrate here that Mn²⁺-doped Prussian blue nanoparticles of ca. 55 nm loaded with doxorubicin may be used as efficient therapeutic agents for combined photothermal and chemo-therapy of cancer cells with a synergic effect under two photon irradiation.

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