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Time‐of‐flight mass spectrometers based on a wedge‐shaped electrostatic mirror with a two‐dimensional field
Rapid Communications in Mass Spectrometry ( IF 1.8 ) Pub Date : 2020-01-15 , DOI: 10.1002/rcm.8590
Igor Spivak‐Lavrov 1 , Orda Baisanov 2 , Evgeniy Yakushev 3 , Leonid Nazarenko 3
Affiliation  

For most of the last two decades, a considerable effort has been made towards improving time‐of‐flight mass spectrometry (TOF MS), which has become an irreplaceable instrumental platform for the purposes of performing analytical measurements in life sciences, such as molecular biology, proteomics, medicine, etc. This can primarily be attributed to the ability of TOF MS to rapidly detect and identify nearly any targeted chemical trace with both high precision and accuracy. However, multi‐span TOF MS experiments are limited due to aberrations arising from multiple reflection; our proposed scheme will minimize these aberrations.

中文翻译:

基于具有二维场的楔形静电镜的飞行时间质谱仪

在过去的二十年中的大部分时间里,人们一直在努力改进飞行时间质谱(TOF MS),这已成为在生命科学(例如分子生物学)中进行分析测量的不可替代的仪器平台,蛋白质组学,医学等。这主要归因于TOF MS能够以高精度和高精度快速检测和识别几乎任何目标化学痕迹的能力。但是,由于多次反射会产生像差,因此多跨度TOF MS实验受到限制。我们提出的方案将使这些像差最小化。
更新日期:2020-01-15
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