![][1] Cells representing a BRCAness phenotype are vulnerable to PARP inhibitors and DNA damaging agents. However, most tumors do not demonstrate a BRCAness phenotype. Although recent studies reveal that BRCAness may be induced through inhibition of CDK12, small-molecule CDK12

中文翻译：

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近期癌症文献集锦


！[] [1]代表BRCAness表型的细胞易受PARP抑制剂和DNA破坏剂的侵害。然而，大多数肿瘤没有表现出BRCAness表型。尽管最近的研究表明BRCAness可能是通过抑制CDK12诱导的，但小分子CDK12