BACKGROUND There is increasing evidence that the substantial global burden of disease for tuberculosis unfolds in concert with dimensions of common mental disorders. Person-centred care holds much promise to ameliorate these comorbidities in low-to-middle income countries (LMICs) and emerging economies. Towards this end, this paper aims to review 1) the nature and extent of tuberculosis and common mental disorder comorbidity and 2) person-centred tuberculosis care in low-to-middle income countries and emerging economies. MAIN TEXT A scoping review of 100 articles was conducted of English-language studies published from 2000 to 2019 in peer-reviewed and grey literature, using established guidelines, for each of the study objectives. Four broad tuberculosis/mental disorder comorbidities were described in the literature, namely alcohol use and tuberculosis, depression and tuberculosis, anxiety and tuberculosis, and general mental health and tuberculosis. Rates of comorbidity varied widely across countries for depression, anxiety, alcohol use and general mental health. Alcohol use and tuberculosis were significantly related, especially in the context of poverty. The initial tuberculosis diagnostic episode had substantial socio-psychological effects on service users. While men tended to report higher rates of alcohol use and treatment default, women in general had worse mental health outcomes. Older age and a history of mental illness were also associated with pronounced tuberculosis and mental disorder comorbidity. Person-centred tuberculosis care interventions were almost absent, with only one study from Nepal identified. CONCLUSIONS There is an emerging body of evidence describing the nature and extent of tuberculosis and mental disorders comorbidity in low-to-middle income countries. Despite the potential of person-centred interventions, evidence is limited. This review highlights a pronounced need to address psychosocial comorbidities with tuberculosis in LMICs, where models of person-centred tuberculosis care in routine care platforms may yield promising outcomes.

中文翻译：

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结核病与常见精神障碍的共病：对中低收入国家和金砖国家的流行病学模式和以人为本的护理干预措施的范围审查。

背景 越来越多的证据表明，结核病的巨大全球疾病负担与常见精神障碍的维度相一致。以人为本的护理在改善中低收入国家 (LMIC) 和新兴经济体的这些合并症方面大有希望。为此，本文旨在回顾 1) 结核病和常见精神障碍合并症的性质和程度，以及 2) 中低收入国家和新兴经济体中以人为本的结核病护理。正文 使用既定指南，针对每个研究目标，对 2000 年至 2019 年在同行评议和灰色文献中发表的英语研究进行了 100 篇文章的范围审查。文献中描述了四种广泛的结核病/精神障碍合并症，即酒精使用和肺结核、抑郁和肺结核、焦虑和肺结核，以及一般心理健康和肺结核。各国的抑郁症、焦虑症、饮酒和一般心理健康的合并症发生率差异很大。酒精使用和肺结核显着相关，尤其是在贫困的背景下。最初的结核病诊断事件对服务使用者产生了重大的社会心理影响。虽然男性倾向于报告更高的酒精使用率和治疗违约率，但女性的心理健康结果通常更差。年龄较大和有精神疾病史也与明显的肺结核和精神障碍合并症有关。几乎没有以人为本的结核病护理干预措施，只有一项来自尼泊尔的研究确定了这一点。结论 在中低收入国家，越来越多的证据描述了结核病和精神障碍合并症的性质和程度。尽管以人为本的干预措施具有潜力，但证据有限。这篇综述强调了在 LMIC 中解决结核病心理社会合并症的明显需求，在这些国家，常规护理平台中以人为本的结核病护理模型可能会产生有希望的结果。