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Beyond Native Deoxyribonucleic Acid, Templating Fluorescent Nanomaterials for Bioanalytical Applications: A Review
Analytica Chimica Acta ( IF 5.7 ) Pub Date : 2020-04-01 , DOI: 10.1016/j.aca.2020.01.023
Taiping Qing , Bo Feng , Peng Zhang , Kaiwu Zhang , Xiaoxiao He , Kemin Wang

Due to its unique programmability, nanosized structure, and biocompatible properties, deoxyribonucleic acid (DNA) has attracted increasing attention for the construction of versatile nanostructures and nanomaterials. This review summarizes the recent developments in DNA-templated fluorescent nanomaterials, including DNA-stabilized quantum dots (QDs) and DNA-templated metal nanoclusters (NCs), as well as their applications in bioanalysis. These fluorescent nanomaterials not only have good fluorescence properties but also exhibit excellent performance in DNA recognition, which greatly expands the range of their bioanalytical applications. Finally, we discuss some current challenges and future work in this field, with the goal of further promoting the potential applications and developments of DNA-templated fluorescent nanomaterials in biochemical analysis.

中文翻译:

除了天然脱氧核糖核酸之外,用于生物分析应用的荧光纳米材料模板化​​:综述

由于其独特的可编程性、纳米结构和生物相容性,脱氧核糖核酸 (DNA) 在构建多功能纳米结构和纳米材料方面引起了越来越多的关注。本综述总结了 DNA 模板荧光纳米材料的最新进展,包括 DNA 稳定量子点 (QD) 和 DNA 模板金属纳米团簇 (NC),以及它们在生物分析中的应用。这些荧光纳米材料不仅具有良好的荧光特性,而且在DNA识别方面表现出优异的性能,极大地扩展了其生物分析应用的范围。最后,我们讨论了该领域当前的一些挑战和未来的工作,
更新日期:2020-04-01
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