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Gingival recession after scaling and root planing with or without systemic metronidazole and amoxicillin: a re-review.
Clinical Oral Investigations ( IF 3.1 ) Pub Date : 2020-01-15 , DOI: 10.1007/s00784-020-03198-4
Manuela E Kaufmann 1 , Daniel B Wiedemeier 2 , Urs Zellweger 3 , Alex Solderer 1 , Thomas Attin 1 , Patrick R Schmidlin 1
Affiliation  

BACKGROUND Gingival recessions inevitably occur during healing after scaling and root planing, but synoptic data on this topic is still lacking. This review compared the recession formation with and without the administration of systemic antibiotics. OBJECTIVES To evaluate the formation of recession with and without the administration of antibiotics during the healing after scaling and root planing. MATERIALS AND METHODS This study re-analyzed publications that reported clinical attachment levels (CAL) and probing pocket depths (PD) up to January 2019, including the pivotal review by Zandbergen and co-workers (2013). Whereas these studies traditionally focused on PD and CAL, the present analysis compared recession formation (ΔREC) after adjunctive systemic administration of amoxicillin (amx) and metronidazole (met) during scaling and root planing (SRP) and SRP alone. The mean increase in ΔREC, if not reported, was calculated from CAL and PD values and statistically analyzed. Recession formation was compared after 3 and 6 months after therapy. Results were separately reported for chronic periodontitis (CP) as well as aggressive periodontitis (AP) cases. RESULTS Recessions increased consistently between baseline and follow-up. In the AP group, median ΔREC was 0.20 mm after 3 months, irrespective of whether antibiotics were administered or not. After 6 months, median ΔREC increased to 0.35 mm after AB and remained stable at 0.20 mm with SRP alone. In the CP group, after 3 months with and without antibiotics, median ΔREC accounted for 0.30 mm and 0.14 mm, respectively. After 6 months, median ΔREC accounted for 0.28 mm (with AB) and 0.20 mm (without AB). The quantitative assessment by meta-analyses also yielded small values (≤ 0.25 mm) for the estimated differences in recession formation between AB and noAB; however, none of them reached statistical significance. CONCLUSIONS Although a slight tendency towards higher recession formation after SRP in combination with AB could be observed in many studies, quantitative meta-analyses showed no clinically relevant difference in recession formation due to the administration of AB. In general, the description and discussion of recessions in the literature seems not to be a major focus so far. CLINICAL RELEVANCE Since the preservation of gingival tissues is important by preventive and therapeutic means, e.g., when avoiding postoperative root sensitivity or performing regenerative surgery, these aspects should not be neglected. We thus suggest to report REC measurements along with PD and CAL values for more direct recession formation (ΔREC) assessments in the future.

中文翻译:

有或没有全身性甲硝唑和阿莫西林的洗牙和根部平整后的牙龈退缩:复查。

背景技术牙龈萎缩不可避免地在结垢和根部刨平后的愈合过程中发生,但是仍然缺乏有关该主题的天气数据。这篇综述比较了使用和不使用全身性抗生素的情况下的衰退形成。目的评估结垢和牙根刨平后愈合过程中是否使用抗生素的情况下凹陷的形成。材料和方法这项研究重新分析了报道截至2019年1月的临床附着水平(CAL)和探查囊袋深度(PD)的出版物,包括Zandbergen及其同事的重要综述(2013)。传统上,这些研究着重于PD和CAL,目前的分析比较了在单独结垢和根部修整(SRP)和SRP期间辅助全身性服用阿莫西林(amx)和甲硝唑(met)后的凹陷形成(ΔREC)。如果未报告,则ΔREC的平均增加值是根据CAL和PD值计算得出并进行统计分析的。治疗后3个月和6个月比较了衰退的形成。分别报告了慢性牙周炎(CP)和侵袭性牙周炎(AP)病例的结果。结果基线和随访之间的衰退持续增加。在AP组中,3个月后的中位ΔREC为0.20 mm,与是否使用抗生素无关。6个月后,AB后中位数ΔREC增加至0.35 mm,仅使用SRP时中值ΔREC保持稳定在0.20 mm。在CP组中,有无抗生素3个月后,中值ΔREC分别为0.30 mm和0.14 mm。6个月后,中位数ΔREC占0.28毫米(使用AB)和0.20毫米(不使用AB)。通过荟萃分析进行的定量评估也得出了AB和noAB之间形成的衰退差异的较小值(≤0.25 mm)。但是,它们都没有达到统计学意义。结论尽管在许多研究中可以观察到SRP与AB联合后出现更高的后退形成的轻微趋势,但定量荟萃分析显示,由于AB的使用,在后退形成方面没有临床相关的差异。总体而言,到目前为止,文献中关于衰退的描述和讨论似乎并不是主要的重点。临床相关性由于牙龈组织的保存通过预防和治疗手段很重要,例如,在避免术后根部敏感性或进行再生手术时,这些方面不应忽略。因此,我们建议报告REC测量值以及PD和CAL值,以便将来进行更直接的衰退形成(ΔREC)评估。
更新日期:2020-01-15
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