Understanding how cytotoxic T cells are regulated is key for enhancing or suppressing their activity in tumor or transplantation settings. A study by Morris et al. (2020) in this issue of Immunity shows that crosslinking of inhibitory Fc receptor FcγRIIb by the suppressive cytokine Fgl2 limits cytotoxic CD8+ T cell responses by inducing T cell apoptosis.

中文翻译：

---

通过FcγRIIb使T-he杀手处于海湾。

了解如何调节细胞毒性T细胞是增强或抑制其在肿瘤或移植环境中活性的关键。Morris等人的研究。（2020）在《免疫》杂志上发表的文章显示抑制性细胞因子Fgl2与抑制性Fc受体FcγRIIb交联，通过诱导T细胞凋亡来限制细胞毒性CD8 + T细胞反应。