Objective Determine whether impairments in lower limb muscle strength exist in individuals with chronic ankle instability (CAI) compared with uninjured controls. Design Systematic review with meta-analysis. Data source A comprehensive search of PubMed, Cochrane, CINAHL, Web of Science and EMBASE electronic databases from inception to 10 February 2019. Eligibility criteria for selecting studies Cross-sectional and case–control studies were included if they objectively measured lower limb muscle strength in individuals with CAI compared with controls. Risk of bias and quality of included studies were assessed. Data of included studies were extracted, and meta-analysis was conducted where appropriate. Results 12 397 unique studies were identified, of which 20 were included and 16 were eligible for meta-analysis. Reviewed studies clearly described the aim/hypothesis and main outcome measure, but most lacked sample size calculation and assessor blinding. Meta-analyses showed individuals with CAI had lower eccentric and concentric evertor strength (30 and 120°/s; Nm; standardised mean difference (SMD) between −0.73 and −0.95), eccentric invertor strength (60 and 120°/s; both Nm and Nm/kg; SMD between −0.61 and −1.37), concentric invertor strength (60 and 120°/s; Nm; SMD=−0.7) and concentric knee extensor strength (SMD=−0.64) compared with control participants. Ankle eccentric dorsiflexor strength was not different between groups. Although pooling was not possible, data from three separate studies indicated that hip flexor, abductor and external rotator strength, but not hip adductor and extensor strength, was lower in individuals with CAI than in control participants. Conclusion Individuals with CAI have ankle inversion and eversion strength deficits. Our data also point to differences between individuals with CAI and controls in hip and knee strength. These elements of the kinetic chain should be evaluated by clinicians who rehabilitate individuals with CAI. PROSPERO registration number CRD42016037759.

中文翻译：

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慢性踝关节不稳与肌肉力量受损有关吗？慢性踝关节不稳患者的踝关节、膝关节和髋关节肌肉力量：荟萃分析的系统评价

目的确定与未受伤的对照组相比，慢性踝关节不稳（CAI）个体是否存在下肢肌肉力量损伤。设计系统回顾与荟萃分析。数据来源 全面搜索 PubMed、Cochrane、CINAHL、Web of Science 和 EMBASE 电子数据库，从开始到 2019 年 2 月 10 日。选择研究的资格标准 如果客观测量下肢肌肉力量，则包括横断面和病例对照研究与对照组相比，患有 CAI 的个体。评估了纳入研究的偏倚风险和质量。提取纳入研究的数据，并酌情进行荟萃分析。结果 确定了 12 397 项独特的研究，其中 20 项被纳入，16 项符合荟萃分析条件。审查的研究清楚地描述了目标/假设和主要结果测量，但大多数缺乏样本量计算和评估者盲法。荟萃分析显示，CAI 个体的离心和向心外翻力量较低（30 和 120°/s；Nm；标准化平均差 (SMD) 在 -0.73 和 -0.95 之间），偏心内翻力量（60 和 120°/s；两者与对照组相比，Nm 和 Nm/kg；SMD 介于 -0.61 和 -1.37 之间）、同心逆变器强度（60 和 120°/s；Nm；SMD=-0.7）和同心膝关节伸肌强度（SMD=-0.64）。踝关节偏心背屈肌强度在各组之间没有差异。尽管不可能进行汇总，但来自三项独立研究的数据表明，髋屈肌、外展肌和外旋肌的力量，而不是髋内收和伸肌的力量，CAI 患者的发病率低于对照组。结论 CAI 患者存在踝关节内翻和外翻力量不足。我们的数据还指出了 CAI 患者与髋关节和膝关节力量控制者之间的差异。对 CAI 患者进行康复治疗的临床医生应评估动力学链的这些元素。PROSPERO 注册号 CRD42016037759。