当前位置: X-MOL 学术ACS Omega › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Optimizing Nanohydroxyapatite Nanocomposites for Bone Tissue Engineering.
ACS Omega ( IF 3.7 ) Pub Date : 2019-12-18 , DOI: 10.1021/acsomega.9b02917
Baboucarr Lowe 1 , John G Hardy 2, 3 , Laurence J Walsh 1
Affiliation  

Bone tissue engineering involves the combined use of materials with functional properties to regenerate bone. Nanohydroxyapatite (nHA) can influence the behavior of cells. The functional and structural properties of nHA can be controlled during nanoparticle synthesis. This review defines the relationship between the attributes of nHA nanoparticles and their biological effects, focusing on biocompatibility, surface-area-to-volume ratio, bonding chemistry, and substrate functionality. The paper explores how these aspects have been applied in the development of scaffolds for the repair of damaged bone or regeneration of missing bone.

中文翻译:


优化骨组织工程的纳米羟基磷灰石纳米复合材料。



骨组织工程涉及结合使用具有功能特性的材料来再生骨。纳米羟基磷灰石(nHA)可以影响细胞的行为。 nHA 的功能和结构特性可以在纳米颗粒合成过程中控制。本综述定义了 nHA 纳米粒子的属性与其生物效应之间的关系,重点关注生物相容性、表面积与体积比、键合化学和基底功能。本文探讨了如何将这些方面应用于开发用于修复受损骨或缺失骨再生的支架。
更新日期:2020-01-14
down
wechat
bug