BACKGROUND Approximately 1 billion people worldwide have Vitamin D deficiency. The aim of this study was to compare Vitamin D status and serum 25-hydroxyvitamin D (25(OH)D) concentrations among adults sampled in the community, in outpatient clinics, as hospital inpatients and in nursing homes in the West of Ireland. The secondary aim was to determine the associations between length of hospital stay (inpatients) at time of serum 25(OH)D sampling and Vitamin D status. METHODS A cross-sectional study was carried out. Patients who had serum 25(OH)D analysis carried out in Galway University Hospitals (January 2011-December 2015) were identified following interrogation of the electronic laboratory data system. Baseline demographics, location and date of sample collection were recorded. Vitamin D deficiency was defined as a serum 25(OH)D concentration<25nmol/L. RESULTS In total, 24,302 patient samples were eligible for inclusion: community n=15,319; outpatient clinics n=6,371; inpatients n=2,339; nursing home residents n=273. Vitamin D deficiency was more common in nursing home residents than inpatients, or those sampled in outpatient clinics or in the community (42%-v-37%-v-17%-v-13%; p<0.001). Inpatients sampled further into their hospital stay (≥3days) had greater Vitamin D deficiency than inpatients sampled on 0-2 days (p=0.007). Season(p<0.001), sex(p<0.001) and age(p<0.001) were associated with 25(OH)D concentrations. Vitamin D deficiency was more common in Winter/Spring, in males and in those aged ≥80years. CONCLUSIONS Nursing home residents and inpatients are at the highest risk for Vitamin D deficiency. Season, sex, age and day of hospital stay on which serum 25(OH)D concentrations were sampled were associated with Vitamin D status.

中文翻译：

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爱尔兰西部社区，门诊，医院和疗养院中成年人的维生素D状况。

背景技术全世界大约有十亿人患有维生素D缺乏症。这项研究的目的是比较爱尔兰西部社区，门诊，住院患者和疗养院中成年人的维生素D状况和血清25-羟基维生素D（25（OH）D）浓度。次要目的是确定血清25（OH）D采样时住院时间（住院患者）与维生素D状态之间的关联。方法进行了横断面研究。在对电子实验室数据系统进行询问之后，确定了在高威大学医院（2011年1月至2015年12月）进行了血清25（OH）D分析的患者。记录基线人口统计，样品收集的地点和日期。维生素D缺乏症定义为血清25（OH）D浓度<25nmol / L。结果总共有24,302个患者样本符合纳入条件：社区n = 15,319；社区n = 15,319。门诊诊所n = 6371; 住院病人n = 2,339; 疗养院居民n = 273。养老院居民中的维生素D缺乏症比住院患者，门诊或社区样本中的维生素D缺乏症更为常见（42％-v-37％-v-17％-v-13％； p <0.001）。住院（≥3天）进一步采样的住院患者维生素D缺乏症比0-2天（p = 0.007）的住院患者高。季节（p <0.001），性别（p <0.001）和年龄（p <0.001）与25（OH）D浓度相关。维生素D缺乏症在冬季/春季，男性和≥80岁的人群中更为常见。结论疗养院居民和住院患者维生素D缺乏症的风险最高。