This review details the challenges with the canonical polymer swelling theory in its ability to accurately estimate realistic polymer swelling behavior. It is important to quantify this behavior since the development of new and hybrid materials with dynamic environmental response is expected to drive rapid growth and innovation in markets including biomedicine, electronics, pharmaceuticals, building and infrastructure, and aerospace. As many of these markets require high precision and controlled dynamic response, hydrogels are being investigated to help address some of the heat transfer and fluid flow challenges found in these applications. Stimuli-responsive materials usually respond to one stimulus (e.g., light, temperature, etc.) However, hybrid polymer materials that respond to multiple stimuli can be developed through the mixing of monomer chains with differing behaviors. For these materials, the synthesis conditions influence the polymer behavior in changing environmental conditions, and it is imperative to develop a deeper understanding of how the preparation of the polymer networks impacts the viscoelastic nature of the polymer. The work also discusses the influence that synthesis conditions have on the behavior of thermo-responsive Poly(N-isopropylacrylamide) (PNIPAAm). Lastly, the paper describes an inferential, nested regression model developed to highlight the dependence the swelling has on the synthesis technique used.

这篇综述详细介绍了规范聚合物溶胀理论在准确估计实际聚合物溶胀行为方面的挑战。量化这种行为非常重要，因为具有动态环境响应的新型和混合材料的开发有望推动包括生物医学，电子，制药，建筑和基础设施以及航空航天在内的市场的快速增长和创新。由于许多这些市场需要高精度和受控的动态响应，因此正在研究水凝胶，以帮助解决这些应用中发现的一些传热和流体流动难题。刺激反应性材料通常会对一种刺激做出反应（例如，光，温度等），但是，可以通过混合具有不同行为的单体链来开发对多种刺激有反应的杂化聚合物材料。对于这些材料，合成条件会在不断变化的环境条件下影响聚合物的行为，因此必须深入了解聚合物网络的制备如何影响聚合物的粘弹性。该工作还讨论了合成条件对热响应性聚（N-异丙基丙烯酰胺）（PNIPAAm）行为的影响。最后，本文描述了一种推理的嵌套回归模型，该模型被开发来强调溶胀对所用合成技术的依赖性。因此，必须深入了解聚合物网络的制备如何影响聚合物的粘弹性。该工作还讨论了合成条件对热响应性聚（N-异丙基丙烯酰胺）（PNIPAAm）行为的影响。最后，本文描述了一个推理的嵌套回归模型，该模型被开发来强调溶胀对所用合成技术的依赖性。因此，必须深入了解聚合物网络的制备如何影响聚合物的粘弹性。该工作还讨论了合成条件对热响应性聚（N-异丙基丙烯酰胺）（PNIPAAm）行为的影响。最后，本文描述了一种推理的嵌套回归模型，该模型被开发来强调溶胀对所用合成技术的依赖性。