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Advances in the scaffolds fabrication techniques using biocompatible polymers and their biomedical application: A technical and statistical review
Journal of Saudi Chemical Society ( IF 5.8 ) Pub Date : 2020-01-13 , DOI: 10.1016/j.jscs.2020.01.002
Adnan Haider , Sajjad Haider , Madhusudana Rao Kummara , Tahseen Kamal , Abdul-Aziz A Alghyamah , Faiza Jan Iftikhar , Bushra Bano , Naeem Khan , Mohammad Amjid Afridi , Sung Soo Han , Ali Alrahlah , Rawaiz Khan

With the advancement in tissue engineering, researchers are working hard on new techniques to fabricate more advanced scaffolds from biocompatible polymers with enhanced porosity, appropriate mechanical strength, diverse shapes and sizes for potential applications in biomedical field in general and tissue engineering in particular. These techniques include electrospinning, solution blow spinning, centrifugal spinning, particulate leaching (salt leaching), freeze-drying, lithography, self-assembly, phase separation, gas foaming, melt molding, 3-D printing, fiber mesh and solvent casting. In this article we have summarized the scaffold’s fabrication techniques from biocompatible polymers that are reported so far, the recent advances in these techniques, characterization of the physicochemical properties of scaffolds and their potential applications in the biomedical field and tissue engineering. The article will help both newcomers and experts working in the biomedical implant fabrication to not only find their desired information in one document but also understand the fabrication techniques and the parameters that control the success of biocompatible polymeric scaffolds. Furthermore, a static analysis of the work published in all forms on the most innovative techniques is also presented. The data is taken from Scopus, restricting the search to biomedical fields and tissue engineering.



中文翻译:

使用生物相容性聚合物的支架制造技术及其生物医学应用的进展:技术和统计评论

随着组织工程学的发展,研究人员正在努力研究新技术,以提高生物相容性的聚合物制成的更先进的支架,该支架具有更高的孔隙率,适当的机械强度,不同的形状和尺寸,可广泛应用于生物医学领域,尤其是组织工程领域。这些技术包括静电纺丝,溶液吹纺,离心纺丝,颗粒浸出(盐浸),冷冻干燥,光刻,自组装,相分离,气体发泡,熔融模塑,3-D打印,纤维网和溶剂浇铸。在本文中,我们总结了迄今已报道的由生物相容性聚合物制成的支架技术,这些技术的最新进展,支架的理化特性的表征及其在生物医学领域和组织工程中的潜在应用。这篇文章将帮助从事生物医学植入物制造的新手和专家不仅在一份文件中找到他们所需的信息,而且还了解控制生物相容性聚合物支架成功的制造技术和参数。此外,还介绍了以各种形式发表的有关最创新技术的作品的静态分析。数据取自Scopus,将搜索范围限制在生物医学领域和组织工程领域。这篇文章将帮助从事生物医学植入物制造的新手和专家不仅在一份文件中找到他们所需的信息,而且还了解控制生物相容性聚合物支架成功的制造技术和参数。此外,还介绍了以各种形式发表的有关最创新技术的作品的静态分析。数据取自Scopus,将搜索范围限制在生物医学领域和组织工程领域。这篇文章将帮助从事生物医学植入物制造的新手和专家不仅在一份文件中找到他们所需的信息,而且还了解控制生物相容性聚合物支架成功的制造技术和参数。此外,还介绍了以各种形式发表的有关最创新技术的作品的静态分析。数据取自Scopus,将搜索范围限制在生物医学领域和组织工程领域。

更新日期:2020-01-13
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