In hematopoietic stem cell transplant recipients, the incidence of tuberculosis in positive interferon-γ release assay (IGRA) without isoniazid prophylaxis (3.58/100 person-years) was higher than in negative or indeterminate IGRA (1.15/100 person-years; P = .01) and in positive IGRA with isoniazid prophylaxis (0/100 person-years; P = .09). The number needed to treat was 22 (95% confidence interval, 12–99) with positive IGRA results.

中文翻译：

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基于同种异体干细胞移植受者γ-干扰素释放测定的潜伏性结核感染治疗。

在造血干细胞移植受者中，未进行异烟肼预防的阳性干扰素-γ释放试验（IGRA）中的结核发生率（3.58 / 100人年）高于阴性或不确定IGRA（1.15 / 100人年；P = .01）和IGRA阳性且预防异烟肼（0/100人年; P = .09）。IGRA结果阳性需要治疗的人数为22（95％置信区间12–99）。