Antibacterial dressing can prevent the occurrence of many infections of wounds. Bacterial cellulose (BC) has the ability to carry and transfer the medicine to achieve a wound healing bandage. In this study, Carbon Quantum Dots-Titanium dioxide (CQD-TiO2) nanoparticles (NP) were added to BC as antibacterial agents. FTIR Spectroscopy illuminated that NPs were well-bonded to BC. Interestingly, MIC test proved that BC/CQD-TiO2 nanostructure (NS) has anti-bacterial properties against Staphylococcus aureus. The findings indicated that, CQD-TiO2 NPs have stronger antibacterial properties with better tensile strength compared to CQD NPs, in a concentration-dependent manner. Toxicity of CQD-TiO2 NPs on human L929 fibroblast cells was also evaluated. Most importantly, the results of the scratch test indicated that the NS was effective in wound healing in L929 cells. The approach in this study may provide an alternative to make an antibacterial wound dressing to achieve an effective drug-based bandage.

中文翻译：

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细菌纤维素CQD-TiO2纳米复合材料的抗菌特性。

抗菌敷料可以防止许多伤口感染的发生。细菌纤维素（BC）具有携带和转移药物以实现伤口愈合绷带的能力。在这项研究中，碳量子点二氧化钛（CQD-TiO2）纳米颗粒（NP）被添加到BC作为抗菌剂。FTIR光谱表明，NP与BC的键合良好。有趣的是，MIC测试证明BC / CQD-TiO2纳米结构（NS）对金黄色葡萄球菌具有抗菌性能。结果表明，与CQD NPs相比，CQD-TiO2 NPs具有更强的抗菌性能和更好的拉伸强度，且呈浓度依赖性。还评估了CQD-TiO2 NP对人L929成纤维细胞的毒性。最重要的是，刮擦试验的结果表明，NS对L929细胞的伤口愈合有效。这项研究中的方法可能会提供一种替代方法来制作抗菌伤口敷料以实现有效的基于药物的绷带。