In the concept of biorefineries, the production of added-value compounds from kraft lignin depolymerization is still hindered by the number of separation processes needed to purify the phenolic compounds. In this work, a sequence of oxidation, membrane filtration and chromatographic separation is proposed for the recovery of vanillin. The alkaline wet oxidation achieved a vanillin yield of 4.3% on lignin weight basis. The two-step membrane filtration reduced the initial organic load to 29.5 (±1.8) g/L in the final permeate. The chromatographic step enriches solutions containing vanillin by alternating the feed phase with desorption utilizing only deionized water. In 22 cycles, 71% of the vanillin fed is recovered with at an average 1.5 g/cycle. Recovered fraction has a vanillin concentration of 4.7 g/L which can be further concentrated. This presents a major breakthrough for vanillin production from oxidized softwood lignin as it simplifies the purification procedure, reducing costs with desorption solvents and avoiding acid use.

在生物精炼厂的概念中，通过硫酸盐木质素解聚生产增值化合物仍然受到纯化酚类化合物所需的分离过程数量的阻碍。在这项工作中，提出了一系列氧化，膜过滤和色谱分离的顺序以回收香兰素。碱性湿式氧化使木质素重量的香草醛收率为4.3％。两步膜过滤将最终渗透物中的初始有机负荷降至29.5（±1.8）g / L。色谱步骤通过仅使用去离子水使进料阶段与解吸交替进行来富集含有香兰素的溶液。在22个循环中，平均以1.5克/循环回收71％的香草醛。回收的级分的香兰素浓度为4.7 g / L，可以进一步浓缩。