The development of inflammatory arthritis in patients receiving immune checkpoint inhibitor therapy is increasingly recognized due to the growing use of these drugs for the treatment of cancer. This represents an important opportunity not only to define the mechanisms responsible for the development of this immune-related adverse event and to ultimately predict or prevent its development, but also to provide a unique window into early events in the development of inflammatory arthritis. Knowledge gained through the study of this patient population, for which the inciting event is known, could shed light into the pathogenesis of autoimmune arthritis. This review will highlight the clinical and immunologic features of these entities to define common elements for future study.

中文翻译：

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免疫检查点抑制剂诱导的炎症性关节炎作为自身免疫性关节炎的模型。

由于越来越多地使用这些药物来治疗癌症，因此越来越多地认识到接受免疫检查点抑制剂治疗的患者会出现炎症性关节炎。这不仅是一个重要的机会，不仅可以定义导致这种免疫相关不良事件发生的机制并最终预测或预防其发生，而且还为了解炎症性关节炎发生的早期事件提供了一个独特的窗口。通过对这一患者群体的研究获得的知识（其诱发事件是已知的）可以揭示自身免疫性关节炎的发病机制。本综述将重点介绍这些实体的临床和免疫学特征，以确定未来研究的共同要素。