Various types of biodegradable polymers containing lactide, glycolide, caprolactone, and trimethylene carbonate units have been used to obtain ciprofloxacin (CFX)‐enriched coatings developed on the Ti6Al7Nb alloy, intended for short‐term therapy. In the first step, the surface of the Ti6Al7Nb alloy was modified, mostly according to sandblasting and anodic oxidation to obtain the TiO₂ layer. Anodizing can be an effective method for preparing TiO₂ coatings with osteoconductive properties. The polymer containing CFX molecules was deposited on the modified alloy, and Polymer + CFX/TiO ₂/Ti6Al7Nb systems were developed. CFX‐enriched coatings adhered well to the surface of the previously modified alloy. Polymer layers maintain the topography of the alloy due to the development of the surface during the sandblasting method. As polymers intended for the study possess degradation ability, they are capable of releasing the incorporated drug. Antibacterial activity of CFX‐enriched coatings was examined to verify the functionality of designed Polymer + CFX/TiO ₂/Ti6Al7Nb systems, and the bactericidal effect was confirmed for all cases. The presented study is an extension of previous, initial research and creates an overview of polyester or polyestercarbonate CFX‐eluting coatings.

中文翻译：

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在 Ti6Al7Nb 种植体上开发抗菌、环丙沙星洗脱生物可降解涂层，以防止种植体周围感染。

含有丙交酯、乙交酯、己内酯和碳酸亚丙酯单元的各种类型的可生物降解聚合物已被用于获得在 Ti6Al7Nb 合金上开发的富含环丙沙星 (CFX) 的涂层，用于短期治疗。第一步，对Ti6Al7Nb合金表面进行改性，主要是通过喷砂和阳极氧化得到TiO ₂层。阳极氧化是制备具有骨传导性能的TiO ₂涂层的有效方法。含有CFX分子的聚合物沉积在改性合金上，Polymer + CFX/TiO ₂ /Ti6Al7Nb 系统被开发出来。富含 CFX 的涂层与先前改性合金的表面粘附良好。由于喷砂方法期间表面的发展，聚合物层保持合金的形貌。由于用于研究的聚合物具有降解能力，它们能够释放掺入的药物。检查了富含 CFX 的涂层的抗菌活性，以验证设计的Polymer + CFX/TiO ₂ /Ti6Al7Nb系统的功能，并证实了所有情况下的杀菌效果。本研究是先前初步研究的延伸，并概述了聚酯或聚酯碳酸酯 CFX 洗脱涂层。